Najib M Rahman
Supernumerary Fellow in Medicine; Associate Professor of Respiratory Medicine, Director, Oxford Respiratory Trials Unit
I am the Tutor in Clinical Medicine at Univ. As such, I provide supervision, coordination and teaching for medical students in their clinical years (years 4 to 6) which includes bedside teaching, pastoral care and careers advice. We have a group of clinicians who provide this teaching across the clinical years.
I also provide tutorials in pathology in the 2nd year, and can provide advice and tutorials in the run up to the FHS.
I direct the Oxford Respiratory Trials Unit, which is one of only a few specialised trials units with a dedicated interest in respiratory disease. We design, coordinate and conduct clinical studies including early phase, translational and multi-centre randomised trials, across a broad spectrum of respiratory disease.
My personal research interest is in pleural disease, and specifically practice changing clinical trials and translational studies in pleural infection, pneumothorax, malignant pleural effusion and empyema.
My group has published more than 80 peer reviewed articles in this field.
Rahman NM, Pepperell J, Rehal S, Saba T, Tang A, Ali N, West A, Hettiarachchi G, Mukherjee D, Samuel J, Bentley A, Dowson L, Miles J, Ryan F, Yoneda K, Chauhan A, Corcoran JP, Psallidas I, Wrightson JM, Hallifax R, Davies HE, Lee YCG, Dobson M, Hedley EL, Seaton D, Russell N, Chapman M, McFadyen BM, Shaw RA, Davies RJO, Maskell NA, Nunn AJ, Miller RF. Effect of Opioids vs NSAIDs and Larger vs Smaller Chest Tube Size on Pain Control and Pleurodesis Efficacy Among Patients With Malignant Pleural Effusion. The TIME1 Randomized Clinical Trial. JAMA 2015 Dec 22-29;314(24):2641-53.
Rahman NM, Maskell NA, Davies CWH, West A, Teoh R, Arnold T, Peckham D, Ali N, Bentley A, McKinlay C, Kinnear W, Wrightson JM, Davies HE, Miller R, Lee YCG, Hedley EL, Crosthwaite N, Choo L, Gleeson FV, Nunn AJ, Davies RJO. Intrapleural Use of Tissue Plasminogen Activator and DNase in Pleural Infection. New England Journal of Medicine 2011;365:518-26
Davies HE, Mishra EK, Kahan BC, Wrightson JM, Stanton AE, Guhan A, Davies CW, Grayez J, Harrison R, Prasad A, Crosthwaite N, Lee YC, Davies RJ, Miller RF, Rahman NM. Effect of an indwelling pleural catheter vs chest tube and talc pleurodesis for relieving dyspnea in patients with malignant pleural effusion: the TIME2 randomized controlled trial. JAMA. 2012 Jun 13;307(22):2383-9.
Rahman NM, Davies HE, Salzberg M, Truog P, Midgely R, Kerr D, Clelland C, Hedley EL, Lee YG, Davies RJ. Use of lipoteichoic acid-T for pleurodesis in malignant pleural effusion: a phase I toxicity and dose-escalation study. Lancet Oncology. 2008, 9(10) 946-952
Rahman NM, Mishra EK, Davies HE, Davies RJ, Lee YC. Clinically Important Factors Influencing the Diagnostic Measurement of Pleural Fluid pH and Glucose. Am J Respir Crit Care Med. 2008 Sep 1;178(5):483-90.
Corcoran JP, Wrightson JM, Belcher E, DeCamp MM, Feller-Kopman D, Rahman NM. Pleural infection: past, present, and future directions. Lancet Respir Med. 2015 Jul;3(7):563-77.
State of the art thoracic ultrasound: intervention and therapeutics. Corcoran JP, Tazi-Mezalek R, Maldonado F, Yarmus LB, Annema JT, Koegelenberg CFN, St Noble V, Rahman NM. Thorax. 2017 Apr 14. pii: thoraxjnl-2016-209340.
Ultrasound in the management of pleural disease. Mercer RM, Psallidas I, Rahman NM. Expert Rev Respir Med. 2017 Apr;11(4):323-331
Provision of Day-Case Local Anesthetic Thoracoscopy: A Multicenter Review of Practice. Psallidas I, Corcoran JP, Fallon J, Bintcliffe O, Sivasothy P, Maskell N, Maldonado F, Pepperell J, Rahman NM. Chest. 2017 Feb;151(2):511-512.
Cost-effectiveness of indwelling pleural catheter compared with talc in malignant pleural effusion. Olfert JA, Penz ED, Manns BJ, Mishra EK, Davies HE, Miller RF, Luengo-Fernandez R, Gao S, Rahman NM. Respirology. 2017 May;22(4):764-770.